3 Steps to Identify Supplements
that Lack Scientific Evidence for their Reported Benefits
by:
Mark Worthen, Psy.D.
This article shows you a simple but
reliable method to identify supplements that do not have scientific
support for their alleged benefits.
Step 1: Go to
http://www.pubmed.org which is a National Library of Medicine
(United States) web site where you can search for articles published in
peer-reviewed scientific journals.
Why check PubMed? Because the National
Library of Medicine carefully selects only high-quality journals that
offer value to medical scientists around the world. Selection criteria
are detailed on this web page:
http://www.nlm.nih.gov/pubs/factsheets/jsel.html
Step 2: Once on the PubMed web
site, search for the generic (scientific) name of the supplement in
question. Supplement manufacturers must list the scientific name for
their supplement's ingredients on the label and in advertisements.
Supplements often contain many ingredients but usually only a few
provide the purported benefits. Those are the ingredients you want to
evaluate--they are often the same ones the manufacturer highlights in
advertisements.
Step 3: This is the step some supplement
companies don't want you to know. Before you click on the "Search"
button at PubMed.org, limit your search to studies that utilize the
right research methodology with the right population.
The right research methodology is a
randomized controlled trial (the double-blind, placebo control group
design fits under this category) and the right population is human
beings.
Specifying human subjects is important
because you want to know if the ingredients in a supplement have been
shown to produce the advertised benefits in real live human beings--not
just in rats pressing levers for food pellets or in a "case study" with
one person.
This is not to say that basic science
research, which is often conducted initially with animals, is
unimportant. On the contrary, such research usually serves as a crucial
building block for subsequent clinical research with humans. But basic
science research does not provide scientific evidence for a supplement's
beneficial health effects on human beings. Only research with human
subjects, using randomized controlled trials, can offer such evidence.
On the PubMed.org search page, click on
the "Limits" tab located under the "Search" box. You will see a number
of drop-down menus. First click on the Publication Type menu and then
select Randomized Controlled Trial. Next click on the drop-down menu
labeled, Humans or Animals and click on Humans.
An Example
Morinda citrifolia is the scientific name
for a popular ingredient in a nutritional supplement. First search on
PubMed for Morinda citrifolia, without placing Limits on your search.
How many results did you receive?
The count was 69 at the time I wrote this
article. Looks impressive, huh?
But now search for Morinda citrifolia
after first placing Limits on the search as described above, so that you
receive only those studies which provide more definitive scientific
evidence for the positive effects of Morinda citrifolia.
How many journal articles did you find
searching with the specified limits? I found 1.
Thus, out of 69 articles found on
PubMed.org, only one provides some evidence for Morinda citrifolia's
beneficial effects. In addition, those results were obtained with a very
specific patient population. Thus, in order to conclude that scientific
evidence exists for Morinda citrifolia's efficacy, scientists would need
to conduct additional randomized controlled trials with diverse patient
populations.
Conclusion
The simple research method described in
this article will help you determine if a given supplement possesses
sufficient scientific evidence for its purported benefits.
Mark Worthen is a
Phi Betta Kappa graduate of the University of Maryland's Honors
Psychology program. He was a Clinical Fellow, Department of Psychiatry,
Harvard Medical School and earned his Doctor of Psychology degree from
Baylor University in 1990. Communicate with Dr. Worthen on the Contact
page of
http://www.Omega-3-Report.com. |